— Collagen induction therapy
Microneedling Treatment
London (Holborn)
4.9
As featured in
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What patients say after being treated at 233 High Holborn.
— Before & after
Real skin,
real results
Before
After
Acne scarring
Microneedling. Smoother, more even texture as remodelled collagen softens the appearance of scars.
Before
After
SkinXcell RF microneedling
Firmer, smoother skin with improved tone and texture after a course of treatments.
Before
After
SkinXcell RF microneedling
Visible lifting and tightening, with a refreshed, more even complexion.
Before
After
Acne scarring & texture
BTL Exion fractional RF, 3 months post-treatment.
Before
After
Fine lines & crepey skin
BTL Exion fractional RF, 3 months post-treatment.
Before
After
Acne scarring & firmness
BTL Exion fractional RF, 1 month post-treatment.
Before
After
Uneven tone & texture
BTL Exion fractional RF, 1 month post-treatment.
Before
After
Congested, uneven skin
BTL Exion fractional RF, 1 month post-treatment.
Before
After
Acne scarring on deeper skin
BTL Exion fractional RF, 6 months post-treatment.
Before
After
Pitted acne scarring
BTL Exion fractional RF, 2 weeks post-treatment.
All photos are of actual patients of London Real Skin and are displayed with their consent. The outcomes shown are relevant only for these patients and do not necessarily reflect the results other patients may experience. Your practitioner will discuss any factors that could influence your own results. Cases marked RF were treated with radiofrequency microneedling, a related but separate treatment.
— Collagen induction therapy in Holborn
Refine Skin Texture and Support Natural Collagen Renewal
Microneedling, or collagen induction therapy, uses ultra-fine medical needles to create controlled microchannels in the skin, triggering the natural repair response that produces new collagen and elastin. At London Real Skin in Holborn, we deliver it with the XCellarisPRO Twist, a German-engineered medical microneedling device, combined with a regenerative serum selected specifically for your skin.
Two things determine the result: the device and what goes into the skin through it. Our practitioners adjust the needle depth across different areas of the face and body, then choose from NCTF, polynucleotides, Purasomes, Calecim Professional or AQ Skin Solutions growth factors depending on your skin’s condition and what you want to change. Every plan begins with a detailed skin assessment.
Treatment areas
Face, neck, décolletage and selected areas of the body
Course
Appointment
Around 60 minutes
From
£340
Microneedling creates controlled microchannels to stimulate the skin’s natural repair and renewal processes.
— The treatment
What Is Microneedling?
Microneedling, also known as collagen induction therapy, uses ultra fine medical-grade needles to create controlled microchannels within the skin. These microscopic injuries activate the natural healing process, encouraging new collagen and elastin as the treated tissue begins to repair.
The depth and intensity can be adjusted according to the area and concern being treated. Rather than removing or resurfacing the entire outer layer, microneedling works within the skin to improve its texture, structure and overall quality over time.
The same microchannels also create a short window in which the skin absorbs active ingredients far more readily than it can through an intact barrier. This is why the serum applied during treatment matters as much as the needling itself — and why we do not use the same product on every client.
— What it treats
What Conditions Can Microneedling Treat?
Microneedling can be used on the face, neck, décolletage and selected areas of the body. Adjustable needle depths allow the procedure to be adapted to delicate areas around the eyes and mouth, broader areas of uneven texture and areas with more established scarring.
— Microneedling can be used to address:
- Acne scarring
- Uneven pigmentation
- Dry skin
- Uneven or rough skin texture
- Sun-damaged skin
- Selected facial and body scars
- Enlarged pores
- Dull or tired-looking skin
— Why patients choose it
What Are the Benefits of Microneedling?
Microneedling encourages natural collagen and elastin renewal without adding volume or changing facial shape. It is a non-surgical, non-ablative treatment that can improve the skin gradually while requiring relatively little interruption to everyday activities.
The benefits of microneedling include
01
Smoother, more refined skin texture
02
Softer-looking acne scars
03
Reduced appearance of fine lines and wrinkles
04
Improved firmness and elasticity
05
Less visible enlarged pores
06
A brighter, more even complexion
07
Adjustable treatment depths for different areas
08
Enhanced delivery of regenerative actives into the skin
09
Treatment for both facial and body concerns
10
Minimal downtime
— The mechanism
How Does Microneedling Work?
01
Inflammatory
Immediate
02
Proliferation
Days to weeks
03
Remodelling
Three to six months
Each microchannel is a controlled, self-limiting injury. The skin responds in three overlapping phases: an immediate inflammatory response, a proliferation phase in which fibroblasts lay down new collagen and elastin, and a remodelling phase in which that new tissue matures and reorganises.
This is why microneedling results are gradual rather than immediate. The redness settles within a day or two, but the remodelling phase continues for months — which is why improvements in texture, firmness and scar appearance develop progressively over the following weeks, and why a course produces more change than a single session.
The XCellarisPRO Twist, a Class IIa medical device made in Germany by Dermaroller GmbH.
— The device
Which Microneedling Device Do We Use? The XCellarisPRO Twist
London Real Skin uses the XCellarisPRO Twist, a medical microneedling device designed and manufactured in Germany.
Every microneedling device creates microchannels. What separates them is how cleanly those channels are made, how consistently the depth is held, and how much collateral trauma is caused along the way.
What this means in practice: the device holds the precision rather than the practitioner’s hand speed, so every pass is consistent. The same clinical standard across the whole treatment area, in every session of your course. Devices such as SkinPen, Dermapen and general-market derma pens all create microchannels, but they differ in retraction mechanism, needle geometry, insertion speed and depth control. Those differences are the reason we chose this one.
Four things led us to this device:
01 / Retrieval
Motor-driven active needle retrieval
02 / Speed
150 insertions per second
03 / Needles
Needle geometry and a flexible needle plate
04 / Control
Precision depth control and sealed sterile modules
— The other half
Microneedling with Serums: The Other Half of the Treatment
Microneedling opens a temporary absorption window. What we put into that window is a clinical decision, and it is where two clients having “the same” treatment end up with genuinely different outcomes.
At London Real Skin we select from five regenerative formulations based on your skin condition, how your skin functions and what you want to achieve. Some clients stay on one product across a course; often the strongest results come from combining them across a planned programme.
01 / Revitalisation
NCTF® — Comprehensive Skin Revitalisation
A skin revitalisation complex with hyaluronic acid alongside more than 50 active ingredients that supports hydration while improving overall skin quality and luminosity.
02 / Repair
Polynucleotides — Supporting Natural Skin Repair
Highly purified DNA fragments that encourage tissue regeneration while helping to calm inflammation. Polynucleotides work by stimulating collagen and improving cellular repair.
Polynucleotides are also available as a standalone injectable treatment.
03 / Exosomes
Purasomes® (DermaFocus) — Advanced Exosome Technology
Purasomes are exosome-based formulations designed to support cellular communication and optimise the skin’s natural regenerative processes.
Microneedling can be combined with a professional exosome-based formulation as part of a separate treatment protocol.
04 / Growth factors
Calecim® Professional — Growth Factors and Signalling Proteins
A blend of growth factors, cytokines and signalling proteins derived from ethically sourced cord-lining technology. These bioactive ingredients support tissue repair, elasticity and post-procedure recovery, with many clients noticing gradual improvement in skin strength and quality across a course.
05 / Signalling
AQ Skin Solutions® — Growth Factor Technology
Growth factor formulations that stimulate the skin’s own regenerative pathways by supporting communication between skin cells, helping build healthier, more resilient skin over time.
— Matching
Which Serum Is Right for Your Skin?
There is no single product that suits everyone. Your practitioner will recommend one, or a combination across your course, at consultation.
This is a guide, not a prescription. The selection is confirmed after your skin assessment.
As a general guide
Dehydration, dullness, prevention
NCTF®
Fragile, reactive or rosacea-prone skin
Polynucleotides
Acne scarring and skin quality
Polynucleotides or Purasomes®
Recovery speed and firmness
Purasomes® or Calecim® Professional
Ageing skin and collagen loss
AQ Skin Solutions® or Calecim® Professional
— Suitability
Am I a Suitable Candidate for Microneedling?
- It may suit you
Microneedling can suit adults who want to address acne scarring, fine lines, pigmentation, enlarged pores, uneven texture or mild skin laxity without undergoing a more intensive resurfacing procedure. It can be used across a broad range of skin tones, with the treatment depth, intensity and aftercare adjusted to the condition and sensitivity of the skin
- It may need to wait
Treatment may need to be postponed if you are pregnant or breastfeeding or have an active skin infection, open wounds or significant inflammation in the treatment area. Your practitioner will review your medical history, current skincare, medications and previous procedures before confirming whether microneedling is appropriate for you.
A personalised microneedling plan can target acne scarring, enlarged pores and uneven skin texture.
— Start to finish
Your Microneedling Journey at London Real Skin
Microneedling creates a controlled injury within the skin, so some temporary reactions are a normal part of recovery. Your practitioner will explain what to expect, discuss any less common risks and provide personalised aftercare guidance during your consultation.
Stage 01
Consultation
During your complimentary consultation, your practitioner will examine your skin, discuss the changes you would like to achieve and review any relevant medical history or previous treatments. You will receive a personalised recommendation covering the treatment area, the serum or combination of serums best suited to your skin, the likely number of sessions, expected recovery and full cost.
Stage 02
Preparing for Treatment
You will normally be advised to avoid retinoids and exfoliating products for seven days before your appointment, protect the skin from excessive sun exposure and arrive with the treatment area in a calm, healthy condition. Blood-thinning medication should only be paused when medically advised by the clinician responsible for your car.
Stage 03
The Microneedling Procedure
A topical anaesthetic is applied for approximately 45 to 60 minutes before the skin is gently cleansed and the treatment areas are mapped. Your practitioner then uses the XCellarisPRO Twist to create precision-controlled microchannels at the required depths, working area by area. Your selected regenerative serum is applied throughout and immediately after needling, while the channels remain open, followed by a soothing mask. The complete appointment generally takes around 60 minutes.
Stage 04
Results
Mild redness is expected during the first one to two days, while the skin can begin to feel smoother and look more refreshed over the following one to two weeks. Visible collagen renewal generally develops from around four to six weeks, with continued improvement possible over three to six months as the skin remodels.
Stage 05
Recovery and Aftercare
Redness, warmth and sensitivity can resemble mild sunburn during the first day or two, with temporary tightness, dryness or light flaking also possible. Keep the skin clean and moisturised for the first 48 hours, avoid makeup, active ingredients and unnecessary sun exposure, use the recommended serums and SPF 30 or higher each day, and avoid swimming, saunas, excessive heat and strenuous exercise for approximately 48 hours.
— Being straight with you
Possible Risks and Side Effects of Microneedling
Microneedling creates a controlled injury within the skin, so some temporary reactions are a normal part of recovery. Your practitioner will explain what to expect, discuss any less common risks and provide personalised aftercare guidance during your consultation.
Short-term effects can include
Redness
Warmth or sensitivity
Mild swelling
Tightness or dryness
Light flaking
Pinpoint bleeding
Temporary bruising
— Cost
How Much Does Microneedling Cost?
The cost of microneedling at London Real Skin depends on the treatment area and whether you book an individual appointment or a course. Treatment packages include your consultation, procedure and recommended aftercare products, with the complete price confirmed before you decide whether to proceed.
— Current microneedling prices include
Microneedling Full Face
£250
Microneedling Full Face, 3 sessions
£675
Microneedling Full Face, 6 sessions
£1,275
Microneedling Localised Area, Small Scar
£200
Microneedling Localised Area, Six Treatments
£1,080
Serum pricing is confirmed at consultation, since the formulation is selected for your skin. Interest-free monthly finance is available. See the full price list for every treatment at the clinic
— The clinic
Why Choose London Real Skin for Microneedling?
At London Real Skin, microneedling is not treated as a standard facial or delivered at the same depth for every client. Our experienced practitioners assess the thickness, sensitivity and overall condition of your skin before adapting the XCellaris Pro Twist settings, supporting products and treatment course to your individual concerns.
Our philosophy is straightforward: healthy skin creates beautiful skin. Rather than pursuing overly aggressive treatments, we focus on improving skin function, supporting natural regeneration and strengthening the skin over time. An approach that produces results that look refreshed and natural rather than overtreated.
Clients choose London Real Skin for
- A dermatology-led treatment environment
- XCellaris Pro Twist microneedling technology
- A choice of five regenerative serums, matched to your skin
- Complimentary consultations
- Ongoing support throughout the treatment course
- A CQC-regulated clinic in Central London
- Experienced aesthetic practitioners
- Adjustable needle depths from 0.25 to 2.5 mm
- Personalised treatment plans
- Clear preparation and aftercare guidance
- Flexible monthly finance options
Book a Microneedling Consultation
Contact London Real Skin today to book a complimentary microneedling consultation at our High Holborn clinic. We will assess your skin, discuss the concerns you want to address and explain the recommended treatment course, expected results, recovery and full cost before creating a personalised plan for smoother, healthier-looking skin.
— Questions
Microneedling FAQs
The questions we are asked most often about the device, the serums, the course and what recovery actually looks like.
What microneedling device does London Real Skin use?
We use the XCellarisPRO Twist, a Class IIa medical microneedling device made in Germany by Dermaroller GmbH. It uses motor-driven active needle retrieval, operates at 150 insertions per second and offers adjustable depth from 0.25mm to 2.5mm with individually sealed, single-use sterile needle modules.
How is the XCellarisPRO Twist different from a SkinPen or Dermapen?
All three are professional microneedling devices that create controlled microchannels, and all can produce good results in trained hands. The differences are mechanical: the XCellarisPRO Twist uses a motor to actively retract the needles on every cycle rather than relying on a spring, runs at 150 insertions per second rather than the 100–120 typical of most pens, and uses cone-shaped needles on a flexible plate that follows the contours of the treatment area. In practice this means cleaner channels, more consistent depth and less surface trauma per pass. We would encourage you to ask any clinic which device they use and why.
Which serum is used during my microneedling treatment?
That depends on your skin. We select from NCTF®, polynucleotides, Purasomes®, Calecim® Professional and AQ Skin Solutions growth factors, or a combination across your course. Your practitioner will recommend the most appropriate option at your consultation based on your skin condition, concerns and goals.
Do the serums make a real difference to the result?
The device creates the stimulus; the serum determines what the skin has to work with while it repairs. Microneedling temporarily increases how readily the skin absorbs actives, so applying a targeted regenerative formulation during that window supports the repair response rather than simply moisturising the surface afterwards.
Does microneedling hurt?
A topical anaesthetic is applied for approximately 45 to 60 minutes before treatment to help keep the procedure comfortable. Most clients notice pressure, vibration or a light scratching sensation, although some areas can feel more sensitive than others.
How many microneedling sessions will I need?
A course of three to six microneedling sessions is often recommended, with appointments generally spaced four to six weeks apart. The exact number will depend on the concern, its severity and how your skin respond.
How quickly will I see microneedling results?
The skin can begin to feel smoother and look more refreshed within the first one to two weeks. More substantial changes linked to collagen renewal generally develop from four to six weeks and can continue over three to six month.
How long do microneedling results last?
Improvements in texture and skin quality can remain visible for an extended period, although the skin will continue to age naturally. Sun exposure, skincare, lifestyle and maintenance treatment can all influence how long the results are retained.
Is microneedling suitable for darker skin tones?
Microneedling can be suitable for a broad range of skin tones because it does not target pigment in the same way as some laser treatments. Careful assessment, suitable treatment settings and consistent sun protection remain important for reducing the risk of irritation or pigmentation changes.
Can microneedling improve acne scars?
Microneedling can soften the appearance of selected indented acne scars by encouraging remodelling within the affected tissue. Deeper, tethered or mixed scar patterns may require additional treatments as part of a combined plan.
Can microneedling reduce enlarged pores?
Microneedling can refine the texture and firmness of the skin surrounding enlarged pores, helping them appear less prominent. It cannot permanently close pores, and genetics, oil production and congestion will continue to influence their appearance.
When can I wear makeup after microneedling?
Makeup should be avoided while the skin is freshly treated and sensitive. Your practitioner will provide specific guidance, but clients are generally advised to wait at least 24 to 48 hours before applying clean, non-irritating products.
What is the difference between microneedling and RF microneedling?
Standard microneedling creates controlled microchannels mechanically, while RF microneedling also delivers radiofrequency energy beneath the skin. RF microneedling is a separate treatment that can be considered for more pronounced laxity or deeper textural concerns.
Can microneedling be combined with exosomes?
Microneedling can be combined with a professional exosome-based formulation as part of a separate treatment protocol. London Real Skin uses Purasomes for clients seeking additional support for skin renewal and recovery.
Treatment areas
RF Microneedling
Radiofrequency energy delivered beneath the skin, for more pronounced laxity and deeper textural concerns.
The Quipment
Our Devices
Every laser, light and radiofrequency platform at the clinic, and what each one is actually for.
The concern
The concern
Acne Scarring
How we assess scar type and severity, and which combination of treatments suits each pattern.
Medical Oversight
Dr Martin Wade
Director, on the GMC specialist register for dermatology.
— Start here
Visit our London skin clinic in Holborn
An in-depth skin analysis with a practitioner who will tell you what will help, what won’t, and what it will cost, before you commit to anything.
Find us
London Real Skin, 233 High Holborn, London WC1V 7DN.
Call 020 7183 5892 or email info@londonrealskin.com.
A short walk from Holborn and Chancery Lane Underground stations.
Opening hours
Monday – Tuesday 09.00 – 17.30
Wednesday – Friday 10.00 – 19.30
Saturday 09.30 – 17.30 · Sunday closed
