— Polynucleotides treatment
Polynucleotides in London
Advanced Skin Regeneration
Restore, repair, and revitalise your skin with polynucleotide treatments in London at London Real Skin. This advanced injectable therapy works at a cellular level to stimulate collagen production, improve skin elasticity, and support natural regeneration—making it an excellent choice for anyone seeking smoother, firmer, and healthier-looking skin without invasive procedures.
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What patients say after being treated at 233 High Holborn.
— Polynucleotide Treatments
What are polynucleotides?
Polynucleotides are highly purified DNA fragments derived from natural sources. When injected into the skin, they activate fibroblasts—the cells responsible for collagen and elastin production— while improving hydration and supporting tissue repair.
This multi-action approach can:
- Smooth fine lines and wrinkles
- Improve skin tone and firmness
- Enhance hydration and radiance
- Repair damage from sun exposure or acne scarring
- Support long-term skin health
Safe, biocompatible, and well-tolerated, polynucleotides are suitable for a wide range of skin types and concerns.
Concerns Treated
Face, Under-eye area, Neck and décolletage, Hands, Localised areas of scarring or sun damage
Course
2–4 sessions, 2–4 weeks apart
Appointment
30-60 minutes
From
Contact clinic
Results
Noticeable results in 4–6 weeks
Downtime
Minimal
— What it treats
What polynucleotides treats
— Polynucleotides can be used to address:
- Face (including cheeks, forehead, and jawline)
- Under-eye area (to improve fine lines and dark circles)
- Neck and décolletage
- Hands
- Localised areas of scarring or sun damage
— Why patients choose it
Benefits of polynucleotide treatments
Our polynucleotide skin treatments in London can deliver:
01
Noticeable, natural skin regeneration
02
Smoother texture and a more even tone
03
Progressive anti-ageing results without synthetic fillers
04
Reduction in acne scars and pigmentation
05
Enhanced hydration and skin resilience
— Suitability
Who is suitable for polynucleotides?
Polynucleotides are ideal for:
- Those noticing early to more advanced signs of ageing
- Anyone seeking subtle, natural skin rejuvenation
- Clients with dehydrated, dull, or uneven skin tone
- Individuals with mild to moderate skin laxity
They may not be suitable if you are pregnant, breastfeeding, have an active skin infection, or certain medical conditions—these will be reviewed during your consultation.
— Start to finish
Your polynucleotides treatment journey at London Real Skin
Step 01
Consultation
We assess your skin and create a tailored treatment plan based on your goals.
Step 02
Treatment
Using fine needles, polynucleotides are injected into targeted areas. The procedure is quick and made comfortable with numbing options.
Stage 03
Recovery & Results
Mild redness or swelling may occur but usually subsides within 24–48 hours. Improvements appear gradually over the following weeks as collagen production increases, with results continuing to develop for up to three months.
— Before and Aftercare
Before & aftercare
Before Treatment:
- Avoid alcohol, anti-inflammatory medication, and blood-thinning supplements for 24–48 hours beforehand (if medically safe)
- Keep your skin hydrated
- Avoid active skincare ingredients for 48 hours prior
After Treatment:
- Avoid makeup for 24 hours
- Apply SPF daily
- Avoid strenuous exercise, saunas, and swimming for 48 hours
- Follow your practitioner’s aftercare advice for the best results
— The clinic
Why choose London Real Skin for polynucleotide treatments?
At London Real Skin, we offer polynucleotide treatments tailored to your individual skin concerns. Using medical-grade formulations, our skilled practitioners work to reverse visible signs of ageing, improve hydration, and repair damage, delivering results that look and feel natural.
Located in central London, our clinic provides a professional and welcoming setting, making it easy to fit your treatments into your schedule while receiving expert, personalised care.
Clients choose London Real Skin for
- A dermatology-led treatment environment
- Complimentary consultations
- Ongoing support throughout the treatment course
- A CQC-regulated clinic in Central London
- Experienced aesthetic practitioners
- Personalised treatment plans
- Clear preparation and aftercare guidance
- Flexible monthly finance options
Book a polynucleotide treatment consultation
If you want to naturally restore your skin’s vitality and achieve a healthier, more youthful complexion, polynucleotide treatments at London Real Skin could be the perfect solution.
Book your consultation today and take the first step towards smoother, firmer, and more radiant skin.
— Questions
Polynucleotides treatment FAQ
The questions we are asked most often about the treatment, the course and what recovery actually looks like.
When will I see results?
Some clients notice improvements within days, but the most significant changes develop after 4–6 weeks.
How many treatments will I need?
A course of 2–4 sessions spaced 2–4 weeks apart is usually recommended.
Are polynucleotides safe?
Yes – when administered by trained professionals, they are safe and well-tolerated.
Is there any downtime?
Minimal—most clients resume normal activities the same day.
Why Choose London Real Skin for Polynucleotides?
- Specialist Expertise – Performed by experienced aesthetic practitioners with advanced injection training
- Customised Approach – Every plan tailored to your skin’s needs and goals
- Central London Location – Easy access with excellent transport links
- Full Support – From consultation through aftercare, we guide you every step of the way
Treatment areas
RF Microneedling
Radiofrequency energy delivered beneath the skin, for more pronounced laxity and deeper textural concerns.
The Quipment
Our Devices
Every laser, light and radiofrequency platform at the clinic, and what each one is actually for.
The concern
The concern
Acne Scarring
How we assess scar type and severity, and which combination of treatments suits each pattern.
Medical Oversight
Dr Martin Wade
Director, on the GMC specialist register for dermatology.
— Start here
Visit our London skin clinic in Holborn
An in-depth skin analysis with a practitioner who will tell you what will help, what won’t, and what it will cost, before you commit to anything.
Find us
London Real Skin, 233 High Holborn, London WC1V 7DN.
Call 020 7183 5892 or email info@londonrealskin.com.
A short walk from Holborn and Chancery Lane Underground stations.
Opening hours
Monday – Tuesday 09.00 – 17.30
Wednesday – Friday 10.00 – 19.30
Saturday 09.30 – 17.30 · Sunday closed
